Thirty percent of the patients never experienced headache from the given dosages. Isosorbide mononitrate (Monoket) is a nitrate vasodilator. In: Current Medical Diagnosis & Treatment 2022. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Ask your pharmacist for a list of the ingredients. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program. It is best not to drink alcohol while you are on isosorbide mononitrate. Available for Android and iOS devices. Treatment and prognosis of heart failure with preserved ejection . Saw palmetto might make your risk of bleeding higher if you also take a blood thinner, such as: It's not suggested to take St. John's wort if you take blood thinners. https://naturalmedicines.therapeuticresearch.com. Isosorbide mononitrate is also sometimes prescribed alongside other medicines for people with heart failure. About one-half of adults in the United States say they have used one or more supplements in the past 30 days. This content does not have an Arabic version. Seek alternatives to the CYP3A4 substrate when possible. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. Do not store in the bathroom. Mayo Clinic does not endorse companies or products. Pricing based on most commonly-filled versions: 180 tablets of isosorbide mononitrate 10mg. government site. On the other hand, the ER version can only help prevent angina. Important information about all medicines, Notes on Isosorbide mononitrate dose and side-effects info, https://patient.info/medicine/isosorbide-mononitrate-elantan-imdur-isotard-monomax-tardisc-xismox, Manufacturer's PIL, Isosorbide mononitrate 10 mg tablets, Carmil XL; Chemydur XL; Elantan LA; Imdur; Isib XL; Ismo; Isodur XL; Isotard XL; Modisal XL; Monomax SR; Monomil XL; Nyzamac SR; Relosorb XL; Tardisc XL; Trangina XL; Xismox XL; Zemon XL, Tablets, modified-release (longer-acting) tablets, and modified-release (longer-acting) capsules, Ask your doctor or pharmacist to recommend a suitable painkiller. Melanoma is one of the most dangerous forms of skin cancer which develops in the skin cells that produce melanin ( the pigment that gives your skin its color). This medicine is a white, round, scored, tablet imprinted with "KU 107" and "20". Isosorbide mononitrate, sold under many brand names, is a medication used for heart-related chest pain ( angina ), heart failure and esophageal spasms. Contraindications: Isosorbide mononitrate should not be used in cases of acute myocardial infarction with low filling pressure, acute circulatory failure (shock, vascular collapse), or hypertrophic obstructive cardiomyopathy (HOCM), constrictive pericarditis, low cardiac filling pressures, aortic/mitral valve stenosis and diseases associated with a raised intra-cranial pressure e.g following a head trauma and including cerebral haemorrhage. https://www.uptodate.com/contents/search. daily and increasing to 40 mg three times daily as necessary, given at 8 AM, 1 PM, and 6 PM), isosorbide mononitrate (starting at 30 mg/day in the morning and increasing to 120 mg/day as necessary), or a transdermal. Be sure to talk to your health care provider before you take any herbal supplements if you take prescription medicines. Prescribed for Angina, Anal Fissure and Nitrate-Induced Headache in Patients with Stable Angina Pectoris: Beneficial Effect of Starting on a Low Dosage. Are you looking for information on isosorbide dinitrate (Isordil) instead? Laboratory and/or medical tests (such as blood pressure) should be performed periodically to monitor your progress or check for side effects. Things to remember when you fill your prescription. To avoid this problem, get up slowly, resting your feet on the floor for a few minutes before standing up. If you suffer headaches when taking Isosorbide mononitrate, be patient. Talk to your doctor about the possible risks of using this medication for your condition. Prescribed for Angina, Heart Failure, Angina Pectoris Prophylaxis. Try our Symptom Checker Got any other symptoms? Swallow the tablet/capsule whole - do not chew or crush it before you swallow. Unless there is a specific reason you need the brand, the generic medication will be a better value. These side effects may go away during treatment as your body adjusts to the medicine. Nitroglycerin works very quickly to widen your blood vessels and help your heart pump blood during a heart attack. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location one that is up and away and out of their sight and reach. This risk may be even higher for certain groups. Do not share this medication with others. Journals of the American College of Cardiology. Some of these medicine interactions can be risky. The effects of this exposure on a nursing infant are unknown. If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088). Headaches can be a sign that the medicine is working, and they might lessen with continued use of the medication. Alcohol will increase the risk of you experiencing side-effects such as feeling dizzy and light-headed. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. Always consult your healthcare provider. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. The information eHealthMe analyzes includes: Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. Herbal supplements can strongly affect the body. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911. [2] It is taken by mouth. 1998 Oct;61(10):577-83. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Your doctor will probably tell you not to take isosorbide if you are taking one of these medications. Consult a doctor or other health care professional for diagnosis and treatment of medical conditions. The narrowing makes it more difficult for blood to flow to your heart muscle. Make sure laboratory personnel and all your doctors know you use this drug. This should pass after a few days. eCollection 2021. View more. This content does not have an English version. Otherwise, call a poison control center right away. May also be prescribed off label for Esophageal Spasm. The two dosage regimens were equally efficient for the relief of angina pectoris without development of tolerance. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. All rights reserved. Isosorbide mononitrate dose and side-effects info | Patient As precautionary measure, breast-feeding should be discontinued during treatment with isosorbide mononitrate. Review/update the May also be prescribed off label for Esophageal Spasm. It took me a few weeks to adapt to it, but the effect on preventing chest pain was dramatic. Accessed Sept. 7, 2022. View interaction reports for isosorbide mononitrate and the medicines listed below. Last Revised - 09/15/2019. The most common side-effect is headache. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Highly clinically significant. Isosorbide mononitrate dose 10 mg twice daily to 120 mg daily in divided doses. Ginkgo. Mayo Clinic offers appointments in Arizona, Florida and Minnesota and at Mayo Clinic Health System locations. Your doctor may recommend treating headaches with an over-the-counter pain reliever (such as acetaminophen, aspirin). Glyceryl trinitrate (GTN) is commonly prescribed for this. Is not subject to the Controlled Substances Act. Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID-19, plus expertise on managing health. Isosorbide extended-release (long-acting) tablets and extended-release capsules are used for the management of chest pain in people who have coronary artery disease. Accessibility Longer-acting tablets and capsules are taken once daily in the morning. Synthroid (levothyroxine) Tylenol (acetaminophen) Vitamin B12 (cyanocobalamin) Vitamin C (ascorbic acid) Vitamin D3 (cholecalciferol) Isosorbide mononitrate disease interactions There are 7 disease interactions with isosorbide mononitrate which include: AMI anemia hemodialysis hypotension intracranial pressure hypertrophic cardiomyopathy glaucoma Isosorbide mononitrate is used to prevent chest pain (angina) in patients with a certain heart condition (coronary artery disease). Your doctor will prescribe you a short-acting nitrate for you to take if this happens. We don't support your browser. Consult your pharmacist or local waste disposal company. Nitrates, although important for the management of angina pectoris, cause significant headache in many patients. Manufacturer's PIL, Imdur 60 mg tablets; TopRidge Pharma Ltd, The electronic Medicines Compendium. Patient aims to help the world proactively manage its healthcare, supplying evidence-based information on a wide range of medical and health topics to patients and health professionals. Your doctor will tell you which is the right dose for you, and this will also be printed on the label of the pack to remind you about what the doctor said to you. Isosorbide controls chest pain but does not cure coronary artery disease. Minimally clinically significant. Isosorbide mononitrate Alternatives Compared Isosorbide mononitrate Aspirin Nitroglycerin Prescription only Prescribed for Angina, Heart Failure, Angina Pectoris Prophylaxis. tell your doctor if you may be dehydrated, if you have recently had a heart attack, or if you have or have ever had heart failure, low blood pressure, or hypertrophic cardiomyopathy (thickening of the heart muscles). What conditions does Isosorbide Mononitrate treat? Cao HY, Wu HD, Song ZK, Tang ML, Yang S, Liu Y, Qin L. Pan Afr Med J. US residents can call their local poison control center at 1-800-222-1222. Enter other medications to view a detailed report. I strongly feel that there is coronary ischemia. Older adults may be more sensitive to the side effects of this medication, especially dizziness and lightheadedness, which could increase the risk of falls. Please note that only the generic name of each medication is listed below. Swallow the extended-release tablets or capsules whole; do not crush, chew, or divide them. Severe postural hypotension with light-headedness and dizziness is frequently observed after the consumption of alcohol. An official website of the United States government. The herb licorice may lower warfarin levels and can add to digoxin's effects. Cardizem Alternatives Compared - Drugs.com Information is also available online at https://www.poisonhelp.org/help. Then, there was a two-week placebo washout, after which the alternative treatment was given. Clipboard, Search History, and several other advanced features are temporarily unavailable. Isosorbide is in a class of medications called vasodilators. All rights reserved. tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Natural Medicines. Manufacturer's PIL, Isosorbide mononitrate 10 mg tablets; Merus Labs Luxco S.a.R.L, The electronic Medicines Compendium. Natural Medicines. It is important that you follow the instructions your doctor gives to you about when to take your doses. Alcohol can make the side effects from isosorbide worse.